CardamomOT ========== .. py:module:: CardamomOT .. autoapi-nested-parse:: CardamomOT ===================================================================================== A gene regulatory network inference method adapted to time-course scRNA-seq datasets. The algorithm consists of calibrating the parameters of a mechanistic model of gene expression. The calibrated model can then be simulated to reproduce the dataset used for inference. The simulation part is based on the Harissa package. Key Features ------------ - Mechanistic inference of gene regulatory networks from scRNA-seq data - Supports time-course and trajectory data - Integration with mechanistic simulation models - Network visualization and analysis tools .. rubric:: References 1. Ventre E, et al. (2021). 2. Ventre E, et al. (2023). 3. Maugé Y. and Ventre E. (2026). CardamomOT: a mechanistic optimal transport-based framework for gene regulatory network inference, trajectory reconstruction and generative modeling. doi: 10.64898/2026.03.31.715390 Author ------ Elias Ventre Yann Mauge License ------- MIT License Submodules ---------- .. toctree:: :maxdepth: 1 /autoapi/CardamomOT/config/index /autoapi/CardamomOT/inference/index /autoapi/CardamomOT/model/index /autoapi/CardamomOT/tools/index